Piraeus is the gateway to Athens , which, in turn, is rightfully considered the center of the centers of the whole world, with the main attraction - the acropolis. Piraeus is an old port city serving the port of Athens, the largest port in Greece to date. Piraeus is part of the great Athens, which boasts an abundance of attractions, including unique monuments of national fine art. More than two hundred museums and galleries, including the University History Museum, the Ceramics Archaeological Museum and many others, will hospitably welcome you within their walls and familiarize themselves with the culture of this area.

Dubrovnik is a Croatian city on the Adriatic Sea. It is one of the most prominent tourist destinations in the Mediterranean Sea, a seaport and the centre of Dubrovnik-Neretva County. Its total population is 42,615 (census 2011). In 1979, the city of Dubrovnik joined the UNESCO list of World Heritage sites.

The prosperity of the city was historically based on maritime trade; as the capital of the maritime Republic of Ragusa, it achieved a high level of development, particularly during the 15th and 16th centuries, as it became notable for its wealth and skilled diplomacy.

In 1991, after the break-up of Yugoslavia, Dubrovnik was besieged by Serbian and Montenegrin soldiers of the Yugoslav People's Army (JNA) for seven months and suffered significant damage from shelling. After repair and restoration works in the 1990s and early 2000s, Dubrovnik re-emerged as one of the top tourist destinations in the Mediterranean.

Kotor is a coastal town in Montenegro. It is located in a secluded part of the Gulf of Kotor. The city has a population of 13,510 and is the administrative center of Kotor Municipality.

The old Mediterranean port of Kotor is surrounded by fortifications built during the Venetian period. It is located on the Bay of Kotor (Boka Kotorska), one of the most indented parts of the Adriatic Sea. Some have called it the southern-most fjord in Europe, but it is a ria, a submerged river canyon. Together with the nearly overhanging limestone cliffs of Orjen and Lovćen, Kotor and its surrounding area form an impressive landscape.

Since the early 2000s Kotor has seen an increase in tourists , many of them coming by cruise ship. Visitors are attracted by the natural environment of the Gulf of Kotor and by the old town of Kotor. Kotor is part of the World Heritage Site dubbed the Natural and Culturo-Historical Region of Kotor.

The fortified city of Kotor was also included in UNESCO's World Heritage Site list as part of Venetian Works of Defence between 15th and 17th centuries: Stato da Terra – western Stato da Mar in 201

Sicily is the largest island in the Mediterranean Sea and one of the 20 regions of Italy. It is one of the five Italian autonomous regions, in Southern Italy along with surrounding minor islands, officially referred to as Regione Siciliana.

Sicily is located in the central Mediterranean Sea, south of the Italian Peninsula, from which it is separated by the narrow Strait of Messina. Its most prominent landmark is Mount Etna, the tallest active volcano in Europe, and one of the most active in the world, currently 3,329 m (10,922 ft) high. The island has a typical Mediterranean climate.

The earliest archaeological evidence of human activity on the island dates from as early as 12,000 BC. By around 750 BC, Sicily had three Phoenician and a dozen Greek colonies and, for the next 600 years, it was the site of the Sicilian Wars and the Punic Wars. After the fall of the Roman Empire in the 5th century AD, Sicily was ruled during the Early Middle Ages by the Vandals, the Ostrogoths, the Byzantine Empire, and the Emirate of Sicily. The Norman conquest of southern Italy led to the creation of the Kingdom of Sicily, which was subsequently ruled by the Hohenstaufen, the Capetian House of Anjou, Spain, and the House of Habsburg. It was finally unified under the House of Bourbon with the Kingdom of Naples as the Kingdom of the Two Sicilies. It became part of Italy in 1860 following the Expedition of the Thousand, a revolt led by Giuseppe Garibaldi during the Italian unification, and a plebiscite. Sicily was given special status as an autonomous region on 15th May 1946, 18 days before the Italian constitutional referendum of 1946. Albeit, much of the autonomy still remains unapplied, especially financial autonomy, because the autonomy-activating laws have been deferred to be approved by the parithetic committee (50% Italian State, 50% Regione Siciliana), since 1946.

Sicily has a rich and unique culture, especially with regard to the arts, music, literature, cuisine, and architecture. It is also home to important archaeological and ancient sites, such as the Necropolis of Pantalica, the Valley of the Temples, Erice and Selinunte.

Naples is the regional capital of Campania and the third-largest municipality in Italyafter Rome and Milan. In 2017, around 967,069 people lived within the city's administrative limits while its province-level municipality has a population of 3,115,320 residents. Its continuously built-up metropolitan area (that stretches beyond the boundaries of the Metropolitan City of Naples) is the second or third largest metropolitan area in Italy and one of the most densely populated cities in Europe.

First settled by Greeks in the second millennium BC, Naples is one of the oldest continuously inhabited urban areas in the world. In the ninth century BC, a colony known as Parthenope or Παρθενόπη was established on the Island of Megaride, later refounded as Neápolis in the sixth century BC. The city was an important part of Magna Graecia, played a major role in the merging of Greek and Roman society and a significant cultural centre under the Romans. It served as the capital of the Duchy of Naples (661–1139), then of the Kingdom of Naples (1282–1816) and finally of the Two Sicilies until the unification of Italy in 1861.

Between 1925 and 1936, Naples was expanded and upgraded by Benito Mussolini's government but subsequently sustained severe damage from Allied bombing during World War II, which led to extensive post-1945 reconstruction work. Naples has experienced significant economic growth in recent decades, helped by the construction of the Centro Direzionale business district and an advanced transportation network, which includes the Alta Velocità high-speed rail link to Rome and Salerno and an expanded subway network. Naples is the third-largest urban economy in Italy, after Milan and Rome. The Port of Naples is one of the most important in Europe and home of the Allied Joint Force Command Naples, the NATO body that oversees North Africa, the Sahel and Middle East.

Naples' historic city centre is the largest in Europe and a UNESCO World Heritage Site, with a wide range of culturally and historically significant sites nearby, including the Palace of Caserta and the Roman ruins of Pompeii and Herculaneum. Naples is also known for its natural beauties such as Posillipo, Phlegraean Fields, Nisida, and Vesuvius.

Neapolitan cuisine is synonymous with pizza – which originated in the city – but it also includes many lesser-known dishes; Naples has the greatest number of accredited stars from the Michelin Guide of any Italian city.

The best-known sports team in Naples is the Serie A club S.S.C. Napoli, two-time Italian champions who play at the San Paolo Stadium in the southwest of the city, in the Fuorigrotta quarter.

Rome is the capital city and a special comune of Italy (named Comune di Roma Capitale). Rome also serves as the capital of the Lazio region. With 2,872,800 residents in 1,285 km2(496.1 sq mi), it is also the country's most populated comune. It is the fourth-most populous city in the European Union by population within city limits. It is the centre of the Metropolitan City of Rome, which has a population of 4,355,725 residents, thus making it the most populous metropolitan city in Italy. Rome is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of the Tiber. The Vatican City (the smallest country in the world) is an independent country inside the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states.

Rome's history spans 28 centuries. While Roman mythology dates the founding of Rome at around 753 BC, the site has been inhabited for much longer, making it one of the oldest continuously occupied sites in Europe. The city's early population originated from a mix of Latins, Etruscans, and Sabines. Eventually, the city successively became the capital of the Roman Kingdom, the Roman Republic and the Roman Empire, and is regarded as the birthplace of Western civilization and by some as the first ever metropolis. It was first called The Eternal City (Latin: Urbs Aeterna; Italian: La Città Eterna) by the Roman poet Tibullus in the 1st century BC, and the expression was also taken up by Ovid, Virgil, and Livy. Rome is also called the "Caput Mundi" (Capital of the World). After the fall of the Western Empire, which marked the beginning of the Middle Ages, Rome slowly fell under the political control of the Papacy, which had settled in the city since the 1st century AD, until in the 8th century it became the capital of the Papal States, which lasted until 1870. Beginning with the Renaissance, almost all the popes since Nicholas V (1447–1455) pursued over four hundred years a coherent architectural and urban programme aimed at making the city the artistic and cultural centre of the world. In this way, Rome became first one of the major centres of the Italian Renaissance, and then the birthplace of both the Baroque style and Neoclassicism. Famous artists, painters, sculptors and architects made Rome the centre of their activity, creating masterpieces throughout the city. In 1871, Rome became the capital of the Kingdom of Italy, which, in 1946, became the Italian Republic.

Rome has the status of a global city. In 2016, Rome ranked as the 14th-most-visited city in the world, 3rd most visited in the European Union, and the most popular tourist attraction in Italy. Its historic centre is listed by UNESCO as a World Heritage Site. The famous Vatican Museums are among the world's most visited museums while the Colosseum was the most popular tourist attraction in world with 7.4 million visitors in 2018. Host city for the 1960 Summer Olympics, Rome is the seat of several specialized agencies of the United Nations, such as the Food and Agriculture Organization (FAO), the World Food Programme (WFP) and the International Fund for Agricultural Development (IFAD). The city also hosts the Secretariat of the Parliamentary Assembly of the Union for the Mediterranean (UfM) as well as the headquarters of many international business companies such as Eni, Enel, TIM, Leonardo S.p.A., and national and international banks such as Unicredit and BNL. Its business district, called EUR, is the base of many companies involved in the oil industry, the pharmaceutical industry, and financial services. Rome is also an important fashion and design centre thanks to renowned international brands centered in the city. Rome's Cinecittà Studios have been the set of many Academy Award–winning movies.

 Barcelona is a city in Spain. It is the capital and largest city of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within city limits, its urban area extends to numerous neighbouring municipalities within the Province of Barcelona and is home to around 4.8 million people, making it the sixth most populous urban area in the European Union after Paris, London, Madrid, the Ruhr area and Milan. It is one of the largest metropolises on the Mediterranean Sea, located on the coast between the mouths of the rivers Llobregat and Besòs, and bounded to the west by the Serra de Collserola mountain range, the tallest peak of which is 512 metres (1,680 feet) high.

Founded as a Roman city, in the Middle Ages Barcelona became the capital of the County of Barcelona. After merging with the Kingdom of Aragon, Barcelona continued to be an important city in the Crown of Aragon as an economic and administrative centre of this Crown and the capital of the Principality of Catalonia. Barcelona has a rich cultural heritage and is today an important cultural centre and a major tourist destination. Particularly renowned are the architectural works of Antoni Gaudí and Lluís Domènech i Montaner, which have been designated UNESCO World Heritage Sites. The headquarters of the Union for the Mediterranean are located in Barcelona. The city is known for hosting the 1992 Summer Olympics as well as world-class conferences and expositions and also many international sport tournaments.

Barcelona is one of the world's leading tourist, economic, trade fair and cultural centres, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. It is a major cultural and economic centre in southwestern Europe, 24th in the world (before Zürich, after Frankfurt) and a financial centre. In 2008 it was the fourth most economically powerful city by GDP in the European Union and 35th in the world with GDP amounting to €177 billion. In 2012 Barcelona had a GDP of $170 billion; and it was leading Spain in employment rate in that moment.

In 2009 the city was ranked Europe's third and one of the world's most successful as a city brand. In the same year the city was ranked Europe's fourth best city for business and fastest improving European city, with growth improved by 17% per year, and the city has been experiencing strong and renewed growth for the past three years. Since 2011 Barcelona has been a leading smart city in Europe. Barcelona is a transport hub, with the Port of Barcelona being one of Europe's principal seaports and busiest European passenger port, an international airport, Barcelona–El Prat Airport, which handles over 50 million passengers per year, an extensive motorway network, and a high-speed rail line with a link to France and the rest of Europe.